| 摘要 |
Compounds represented by general formula (1) or salts thereof; and drugs containing the same as the active ingredient. Because of having potent squalene synthetase inhibitory effects, these compounds are useful as remedies or preventives for hypercholesterolemia, etc. In said formula, X1 represents esterifiable carboxy, etc.; Y1 represents a single bond, etc.; at least one of A1, A2 and A3 represents: -R2-a1-R3-a2, wherein R2 represents a divalent hydrocarbon group; R3 represents a single bond etc.; a1 and a2 represent each a single bond, -S-, etc.; and represents the bond to Q1, Q2 or Q3; while the remainder(s) represent: -R8-a3-R9-a4, wherein R8 and R9 represent each a single bond, etc.; a3 and a4 represent each a single bond, -S-, etc.; and represents the bond to Q1, Q2 or Q3; and at least one of Q1, Q2 and Q3 represents cyclic hydrocarbyl, etc., while the remainder(s) represent hydrogen, etc.
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