| 摘要 |
<p>Compounds represented by general formula (1) or salts thereof; and drugs containing the same as the active ingredient. Because of having potent squalene synthetase inhibitory effects, these compounds are useful as remedies or preventives for hypercholesterolemia, etc. In said formula, X1 represents esterifiable carboxy, etc.; Y1 represents a single bond, etc.; at least one of A?1, A2 and A3¿ represents: -R?2-a1-R3-a2¿→, wherein R2 represents a divalent hydrocarbon group; R3 represents a single bond etc.; a?1 and a2¿ represent each a single bond, -S-, etc.; and → represents the bond to Q?1, Q2 or Q3¿; while the remainder(s) represent: -R?8-a3-R9-a4¿→, wherein R?8 and R9¿ represent each a single bond, etc.; a?3 and a4¿ represent each a single bond, -S-, etc.; and → represents the bond to Q?1, Q2 or Q3¿; and at least one of Q?1, Q2 and Q3¿ represents cyclic hydrocarbyl, etc., while the remainder(s) represent hydrogen, etc.</p> |
