| 发明名称 |
Metalloproteinase inhibitors pharmaceutical compositions containing them and their use |
| 摘要 |
The present invention is directed to compound of formula (I), wherein R1, R2, R3, R4, R5, , and (Ia) are as defined herein. These compounds are useful for inhibiting the activity of a mctalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds. |
| 申请公布号 |
ZA9709406(B) |
申请公布日期 |
1998.07.09 |
| 申请号 |
ZA19970009406 |
申请日期 |
1997.10.21 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC.;SYNTEX (U.S.A.) INC. |
发明人 |
STEVEN L. BENDER;ARLINDO L. CASTELHANO;WESLEY K. M. CHONG;MELWYN A. ABREO;ROLAND J. BILLEDEAU;JIAN JEFFREY CHEN;JUDITH G. DEAL |
| 分类号 |
A61K;A61K31/34;A61K31/38;A61K31/40;A61K38/05;C07C;C07D;C07D207/327;C07D207/337;C07D231/12;C07D233/56;C07D307/54;C07D333/24;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07K5/078 |
主分类号 |
A61K |
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