发明名称 HYDROPHOBIC SILICA ADSORBENTS FOR LIPIDS
摘要 <p>There is provided a process for the preparation of a highly reactive hydrophobic silica capable of lipophilic binding of lipids present in aqueous media, in particular body fluids. The hydrocarbon substituted silica utilized in the first step of this process may be prepared from hydrophilic silica, suitably pyrogenic silica. This is then treated with a volatile hydrocarbon substituted silicon compound. The next step of the process comprises treating the substituted hydrophobic silica with an alcohol. In order to enable the thus produced material to selectively adsorb lipids in the presence of protein, to the substantial non absorption of the proteins (other than lipoproteins), a further step is carried out. This comprises treating with aqueous ammonia or amines wherein substituents on the amine nitrogen may be the same or different. Also included in the scope of the present invention is the use of the above materials in procedures for absorbing lipids from aqueous media, suitably body fluids both together with and to the substantial exclusion of proteins.</p>
申请公布号 WO1998029187(A1) 申请公布日期 1998.07.09
申请号 US1997018748 申请日期 1997.10.16
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