| 摘要 |
<p>Methods for classifying large numbers of proteins contained in a collection of interest are described. The collection may represent the repertoire of proteins encoded by the genome of an organism including a higher organism or those expressed by a particular tissue or type of cell. Classification is based on ability to bind ligands contained in a panel representative of the range of physiological interactions. The methods of the invention may also be used to evaluate relative binding of proteins in a set of proteins with respect to a physiologically significant ligand so as to permit the modification of specificity of a desired ligand/receptor interaction.</p> |
