发明名称 |
TRANSCYTOSIS VEHICLES AND ENHANCERS FOR DRUG DELIVERY |
摘要 |
Transcytosis of a physiologically-active agent that exerts its action following passage across endothelia, epithelia or mesothelia containing the GP60 receptor is enhanced by formulation with or conjugation to a transcytosis enhancer or vehicle selected from albumin and fragments thereof, anti-GP60 antibody and fragments thereof, GP60 peptide fragments, and PDI (protein disulphide isomerase) and fragments thereof. |
申请公布号 |
EP0851767(A1) |
申请公布日期 |
1998.07.08 |
申请号 |
EP19960931162 |
申请日期 |
1996.09.20 |
申请人 |
ANDARIS LIMITED |
发明人 |
SUTTON, ANDREW, DEREK;MALIK, ASRAR BARI;TIRUPPATHI, CHINNASWAMY;JOHNSON, RICHARD, ALAN |
分类号 |
A61K47/42;A61K38/00;A61K47/48;C07K14/705;C12N5/08 |
主分类号 |
A61K47/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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