| 摘要 |
<p>N,N'-bis-(alkoxyalkyl)pyridine-2,4-dicarboxylic acid diamides of common formula (I), wherein R1 and R2' represent linear or branched C1-C4-alkylene, R2 and R2' represent unbranched C1-C4-alkyl or a hydrogen atom, n and n' are 1 or 2, wherein R1 a R1', R2 a R2', n and n' are identical or different, a method of preparation thereof, in reaction of halogenide pyridine-2,4-dicarboxylic acid with alkoxylalkylamine or hydroxyalkylamine. These compounds inhibit prolin hydroxylase and lysin hydroxylase and are suitable as fibrosuppressants and immunosuppressants. Pharmaceutical agents containing said compositions are also described.</p> |
