发明名称 |
Cyclic peptide compounds for pain treatment and their production process |
摘要 |
<p>This invention provides processes for producing novel cyclic peptide compounds, which comprise cultivating Ctenomyces serratus FERM BP-5731 and then isolating the cyclic peptide compounds from the fermentation broth. The compounds produced by these processes include a cyclic peptide compound of the following formula (I): <CHEM> The present invention also relates to a pharmaceutical composition comprising the same, which is useful in the treatment of severe pain, detoxication of narcotics dependency or acute narcotics intoxication or the like.</p> |
申请公布号 |
EP0852232(A1) |
申请公布日期 |
1998.07.08 |
申请号 |
EP19970309757 |
申请日期 |
1997.12.03 |
申请人 |
PFIZER INC.;PFIZER PHARMACEUTICALS INC. |
发明人 |
HIRAI, HIDEO;KOJIMA, NAKAO;NISHIDA, HIROYUKI;SAITO, TOSHIYUKI;YOSHIKAWA, NOBUJI |
分类号 |
C12P21/04;A61K38/00;A61P25/04;A61P25/30;A61P39/02;C07K5/12;C12P21/02;C12R1/645;(IPC1-7):C07K5/12;A61K38/12 |
主分类号 |
C12P21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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