发明名称 |
Di-substituted 1,2-dioxetane compounds having increased water solubility and assay compositions |
摘要 |
Stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility are provided. Dioxetanes further instituted with two or more water-solubilizing groups disposed on the dioxetane structure provide superior performance by eliminating the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. Compositions comprising a dioxetane with two or more water-solubilizing groups, a non-polymeric cationic surfactant enhancer and optionally a fluorescer, for providing enhanced chemiluminescence are also provided.
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申请公布号 |
US5777135(A) |
申请公布日期 |
1998.07.07 |
申请号 |
US19950509305 |
申请日期 |
1995.07.31 |
申请人 |
LUMIGEN, INC.;BOARD OF GOVERNORS WAYNE STATE UNIV. |
发明人 |
AKHAVAN-TAFTI, HASHEM;DE SILVA, RENUKA;SCHAAP, A. PAUL |
分类号 |
G01N33/535;C07C69/00;C07D321/00;C07F9/12;C07F9/655;C09K11/06;C09K11/07;G01N33/53;G01N33/543;G01N33/58;(IPC1-7):C07D321/00;C07C69/76;C07F9/02 |
主分类号 |
G01N33/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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