发明名称 HUMAN GROWTH HORMONE
摘要 PROBLEM TO BE SOLVED: To obtain a human growth hormone having suppressing action on the growth of tumor such as breast cancer in the presence of oestrogen and capable of being used as a tumor growth-suppressing agent, etc., by making the human growth hormon include a human growth hormone having a specific molecular weight as an active ingredient. SOLUTION: This human growth hormone is obtained by having a human growth hormone having an amino acid sequence represented by formula I or formula II and having about 20,000 molecular weight as an active ingredient, compounding the growth hormone with a generally permissible medicinal additive, e.g. D-mannitol as an isotonic agent and preparing the mixture. The growth hormone can be used as a tumor growth suppressing agent, etc., excellent as a medicinal composition having suppressing action on growth of breast cancer, etc., developing growth hormone receptor or prolactin receptor in the presence of am estrogen.
申请公布号 JPH10182699(A) 申请公布日期 1998.07.07
申请号 JP19960347433 申请日期 1996.12.26
申请人 MITSUI CHEM INC 发明人 NAKAJIMA KUNIO;ASADA NORIAKI;HONJO MASARU
分类号 C12P21/02;A61K38/27;A61P35/00;C07K14/61;C12R1/185;(IPC1-7):C07K14/61 主分类号 C12P21/02
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