发明名称 |
Phosphocholines of retinoids |
摘要 |
Novel retinoid phosphocholines are disclosed having the general Formula (I): <IMAGE> wherein R represents a retinyl or retinoyl moiety. The optical and geometric isomers of compounds of Formula (I) and the pharmaceutically-acceptable salts thereof, are also disclosed. The subject compounds exhibit anti-tumor, anti-psoriatic and anti-inflammatory activities in addition to their inherent Vitamin A-like activities. The invention embraces the novel compounds, pharmaceutical compositions thereof, and methods of using the same.
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申请公布号 |
US5776915(A) |
申请公布日期 |
1998.07.07 |
申请号 |
US19970910191 |
申请日期 |
1997.08.12 |
申请人 |
CLARION PHARMACEUTICALS INC. |
发明人 |
PETERSON, ANDREW C.;NAIR, HARIDASAN K. |
分类号 |
A61K9/127;C07F9/09;C07F9/117;(IPC1-7):A61K31/685;C07F9/10 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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