Peripheral benzodiazepine receptor ligands as antiinflammatory agents
摘要
Compounds which bind with high affinity to peripheral benzodiazepine receptors are useful as antiinflammatory agents. Such compounds include isoquinoline and benzodiazepine derivatives, such as PK 11195. A method of treating an inflammatory condition in a mammal with such compounds is provided. Pharmaceutical compositions comprising such compounds are provided. A method is provided for identifying compounds that are therapeutically effective for treating inflammatory conditions.
申请公布号
US5776946(A)
申请公布日期
1998.07.07
申请号
US19950520211
申请日期
1995.08.28
申请人
MCGEER, PATRICK L.;WATERFIELD, J. DOUGLAS;MCGEER, EDITH G.
发明人
MCGEER, PATRICK L.;WATERFIELD, J. DOUGLAS;MCGEER, EDITH G.