| 摘要 |
A novel method for preparing optically active chlorohydrin compound and optically active 1,2-diol compound and/or optically active 3-hydroxy- gamma -butyrolactone which are useful as intermediates for preparing medicaments, agricultural chemicals, physiologically active substances and ferroelectric liquid crystals, which comprises treating a racemic chlorohydrin compound having the formula: <IMAGE> wherein R1 is H or lower alkyl group; and R2 is substituted or unsubstituted lower alkyl group when R1 is H; or R2 is H when R1 is lower alkyl group with a microorganism, whereby selectively degrading only one of optical isomers thereof, and recovering the remaining an other optically active chlorohydrin and isolating optically active 1,2-diol compound and/or optically active 3-hydroxy- gamma -butyrolactone converted by the reaction.
|
