发明名称 Polyprolyl inhibitors of cyclophilin
摘要 This invention relates to neurotrophic low molecular weight, small molecule peptidic cyclophilin inhibitor compounds having an affinity for cyclophilin-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
申请公布号 AU5702698(A) 申请公布日期 1998.07.03
申请号 AU19980057026 申请日期 1997.12.08
申请人 GUILFORD PHARMACEUTICALS INC. 发明人 GREGORY S. HAMILTON;LING WEI;JOSEPH P. STEINER
分类号 A61K45/00;A61K38/07;A61K38/08;A61K38/55;A61P25/00;A61P25/16;A61P25/28;C07K5/10;C07K7/06 主分类号 A61K45/00
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