发明名称 |
PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES |
摘要 |
A process for the preparation of heteroaryl-phenylalanines of formula (II) in which R is a hydrogen atom, a straight or branched C1-C4 alkyl groups or a benzyl group; R1 is an optionally substituted 5 or 6 membered aromatic heterocyclic group with one or two heteroatoms selected among nitrogen, oxygen and sulphur; comprising a cross-coupling reaction among heteroaryl-zinc halide and phenylalanine derivatives is described. Compounds of formula (II) are intermediates useful for the preparation of compounds endowed with pharmacological activity.
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申请公布号 |
WO9828284(A1) |
申请公布日期 |
1998.07.02 |
申请号 |
WO1997EP07024 |
申请日期 |
1997.12.15 |
申请人 |
ZAMBON GROUP S.P.A.;VILLA, MARCO;PAIOCCHI, MAURIZIO;ARRIGHI, KATIUSCIA |
发明人 |
VILLA, MARCO;PAIOCCHI, MAURIZIO;ARRIGHI, KATIUSCIA |
分类号 |
C07D213/55;C07D239/26;C07D241/12;C07D277/20;C07D277/30;C07D307/54;C07D333/24;(IPC1-7):C07D277/30 |
主分类号 |
C07D213/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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