CATIONIC FILM-FORMING POLYMER COMPOSITIONS CONTAINING SAME, AND USES THEREOF, INCLUDING TOPICAL DELIVERY SYSTEM AND METHOD OF DELIVERING AGENTS TO THE SKIN AND HAIR

摘要

A mixture of lipophilic and amphiphilic/hydrophilic film-forming polymers of the formula (I) R-(CO)mY<1>-(CH2CHR<1>O)n- [CONH-Z-NHCO(OCH2CHR<2>)n'-Y<2>-(CH2CHR<2>O)n'']p -CONH-Z-NHCO-(OCH2CHR<1>)n-Y<1>(CO)mR where R represents (i) an alkyl, alkenyl or alkaryl group of from 1 to 30 carbon atoms or (ii) a polypropylene oxide group or polybutylene oxide group; R<1> and R<2>, each, independently, represent a hydrogen atom, or a methyl or ethyl group; Z represents a divalent linking hydrocarbyl group; m is 0 or 1; when m = 0, Y<1> represents O, NR<3> or N<+>R<3>R<4>X<-> and when m = 1 Y<1> represents O; Y<2> represents O, NR<3>, N<+>R<3>R<4>X<->, (R<3>NCH2CH2)t, or [(R<3>R<4>N<+>CH2CH2)X<->]t; R<3> and R<4>, independently, represent C1-C22 alkyl; X represents an anion; t is a positive integer; n and n', are each, independently, a positive number and p is >0, provide a skin substantive, occlusive moisture barrier covering for skin or hair. When Y<1> and Y<2> are O the polymers are nonionic in character when Y<1> or Y<2> represents NR<3> or N<+>R<3>R<4>X<-> the polymers are cationic in character. The compositions have a moisturizing effect by reducing transepidermal water loss. The lipophilic or amphiphilic or hydrophilic film-forming polymers may be used individually or as mixtures as a delivery system for delivering pharmacological or cosmetic agents to the skin or hair.