发明名称 |
INDANE OR DIHYDROINDOLE DERIVATIVES |
摘要 |
The present invention relates to substituted indane or dihydroindole compounds of Formula (I), wherein A and B are independently O or S; D is an optionally substituted methylene group; X is N or optionally substituted C; and W is a spacer group. The compounds are either selective dopamine D4 ligands or they have combined effects at dopamine D4 and serotonergic receptors and/or the serotonergic transporter. These compounds are therefore useful in the treatment of certain psychiatric and neurologic disorders, including psychosis, depression and anxiety.
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申请公布号 |
CA2275299(A1) |
申请公布日期 |
1998.07.02 |
申请号 |
CA19972275299 |
申请日期 |
1997.12.19 |
申请人 |
H. LUNDBECK A/S |
发明人 |
PEDERSEN, HENRIK;MIKKELSEN, IVAN;PERREGAARD, JENS KRISTIAN |
分类号 |
A61K31/496;A61P9/10;A61P25/06;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;C07D317/66;C07D405/12;C07D409/12;(IPC1-7):C07D317/66;A61K31/495 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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