发明名称 |
AROMATIC AMINE DERIVATIVES HAVING NOS INHIBITORY EFFECT |
摘要 |
Compounds represented by general formula (1) which have NOS inhibitory activities and are useful as drugs, for example, remedies for cerebrovascular disorders, wherein R1 and R2 represent each hydrogen, etc.; R3 and R4 represent each hydrogen, lower alkyl, etc.; R5 represents hydrogen, etc.; X1, X2, X3 and X4 represent each hydrogen, lower alkoxyl, etc.; A represents an optionally substituted pyridine ring, etc.; and m and n are each 0 or 1. |
申请公布号 |
WO9828257(A1) |
申请公布日期 |
1998.07.02 |
申请号 |
WO1997JP04762 |
申请日期 |
1997.12.24 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;ESAKI, TORU;MAKINO, TOSHIHIKO;NISHIMURA, YOSHIKAZU;NAGAFUJI, TOSHIAKI |
发明人 |
ESAKI, TORU;MAKINO, TOSHIHIKO;NISHIMURA, YOSHIKAZU;NAGAFUJI, TOSHIAKI |
分类号 |
C07C215/56;A61K31/137;A61K31/40;A61K31/44;A61K31/4965;A61K31/50;A61K31/505;A61P9/10;C07C209/10;C07C211/55;C07C211/56;C07C217/92;C07C229/58;C07C229/60;C07C271/20;C07C323/09;C07D207/34;C07D207/42;C07D213/74;C07D213/75;C07D213/76;C07D213/78;C07D213/80;C07D213/803;C07D213/82;C07D213/85;C07D231/14;C07D231/16;C07D237/12;C07D237/20;C07D237/24;C07D239/42;C07D241/16;C07D241/24;C07D263/48;C07D277/42;C07D521/00 |
主分类号 |
C07C215/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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