发明名称 AROMATIC AMINE DERIVATIVES HAVING NOS INHIBITORY EFFECT
摘要 Compounds represented by general formula (1) which have NOS inhibitory activities and are useful as drugs, for example, remedies for cerebrovascular disorders, wherein R1 and R2 represent each hydrogen, etc.; R3 and R4 represent each hydrogen, lower alkyl, etc.; R5 represents hydrogen, etc.; X1, X2, X3 and X4 represent each hydrogen, lower alkoxyl, etc.; A represents an optionally substituted pyridine ring, etc.; and m and n are each 0 or 1.
申请公布号 WO9828257(A1) 申请公布日期 1998.07.02
申请号 WO1997JP04762 申请日期 1997.12.24
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA;ESAKI, TORU;MAKINO, TOSHIHIKO;NISHIMURA, YOSHIKAZU;NAGAFUJI, TOSHIAKI 发明人 ESAKI, TORU;MAKINO, TOSHIHIKO;NISHIMURA, YOSHIKAZU;NAGAFUJI, TOSHIAKI
分类号 C07C215/56;A61K31/137;A61K31/40;A61K31/44;A61K31/4965;A61K31/50;A61K31/505;A61P9/10;C07C209/10;C07C211/55;C07C211/56;C07C217/92;C07C229/58;C07C229/60;C07C271/20;C07C323/09;C07D207/34;C07D207/42;C07D213/74;C07D213/75;C07D213/76;C07D213/78;C07D213/80;C07D213/803;C07D213/82;C07D213/85;C07D231/14;C07D231/16;C07D237/12;C07D237/20;C07D237/24;C07D239/42;C07D241/16;C07D241/24;C07D263/48;C07D277/42;C07D521/00 主分类号 C07C215/56
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