| 摘要 |
<p>The present invention provides a virus-like particle for use in the treatment or prevention of at least a microorganism infection wherein said particle comprises: at least an antigenic and/or immunogenic polypeptide or part thereof from the microorganism, fused to at least the last 19 amino acid of the COOH terminal sequence of the large protein from Hepatitis D virus (L-HDAg), wherein the fusion protein is at least partially enveloped by Hepatitis B surface antigen (HBsAg).</p> |
