发明名称 METHOD FOR PREPARING A TETRAHYDROPYRIDIN DERIVATIVE
摘要 The invention concerns a method for preparing 1-¢2-(2-naphthyl)ethyl!-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin of formula (I) and its pharmaceutically acceptable salts by reacting 2-(2-bromoethyl)naphthalene with 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin or one of its salts, and a global method for preparing the same product and its salts by reduction of naphthylacetic acid, treatment of the resulting 2-naphthylethanol with hydrobromic acid and treatment of 2-(2-bromoethyl)naphthalene with 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin or one of its salts.
申请公布号 CA2275592(A1) 申请公布日期 1998.07.02
申请号 CA19972275592 申请日期 1997.12.23
申请人 SANOFI 发明人 BUJ, MICHEL;FILHOL, ROBERT
分类号 C07C17/16;C07D211/70;(IPC1-7):C07D211/70;A61K31/44 主分类号 C07C17/16
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