发明名称 |
New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins ((basic)-N-substituted and (basic)-N,N-disubstituted derivatives of 2,6-diamino-thiazolo(4,5-f)indan and 2,7-di-amino-thiazolo(4,5-g)tetralin |
摘要 |
The invention relates to 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins having general formula (1): wherein R1 and R2, which may be identical or different, are selected from the group consisting of a hydrogen atom, alkyl or haloalkyl groups of 1 to 7 carbon atoms, (alkyl)cycloalkyl groups of 3 to 7 carbon atoms, alkenyl or alkynyl groups of 3 to 6 carbon atoms, arylalkyl having 1 to 3 carbon atoms in the alkyl moiety, while the aryl nucleus may be substituted; and n and m are 1 or 2; and the enantiomers and the acid addition salts thereof, pharmaceutical compositions containing them and their use in the preparation of medicaments having an effect on the dopaminergic system of the central nervous system and/or the circulation. |
申请公布号 |
SE9802360(D0) |
申请公布日期 |
1998.07.01 |
申请号 |
SE19980002360 |
申请日期 |
1998.07.01 |
申请人 |
HAAKAN VILHELM WIKSTROEM |
发明人 |
PER ERIK *ANDREN;PER ARVID EMIL *CARLSSON;DURK *DIJKSTRA;LARS *GUNNE;LEONARD ALEXANDER VAN *VLIET;HAAKAN VILHELM *WIKSTROEM |
分类号 |
A61K31/428;A61P25/00;A61P25/16;A61P25/18;A61P25/30;C07D277/60;C07D277/84;(IPC1-7):C07D/ |
主分类号 |
A61K31/428 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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