CUSTOMIZED OLIGONUCLEOTIDE MICROCHIPS AS MULTIPLE BIOSENSORS

摘要

Biosensors are constructed using customized micromatrices to design a microship. The microchip contains an arrangement of oligonucleotides designed to provide information on oligonucleotide sequences in a sample to be tested by the ability of the oligonucleotides in the nucleic acid sample to hybridize with oligonucleotides on the microchip. Biosensors are used to detect microorganisms in the environment, in biological samples and in food. Biosensors are also used to diagnose genetic defects, to identify polymorphisms, and to monitor quantitative gene expression.