PROCESS FOR PRODUCING A TRANSDERMAL THERAPEUTIC SYSTEM WITH A PHASED RELEASE OF ACTIVE SUBSTANCE

摘要

The invention refers to the preparation of transdermal system with a phased release of the active substance and to its use for the local and systemic dermal application of the active substance in human or veterinary medicine or in the cosmetics industry. It consists of the upper layer that is not in contact with the skin and is impermeable to the active substance(s), of the reservoir which contains the membrane and of the layer that sticks to the skin with the removable protective foil. This enables higher initial doses of the active substance and lower maintenance doses, which depends on the characteristics of the membrane.