发明名称 |
Immune reactivity to expressed activated oncogenes for diagnosis and treatment of malignancy |
摘要 |
Methods for the detection, monitoring and treatment of malignancies are disclosed. Detection of the proliferation of T cells in response to in vitro exposure to a protein expression product of an activated oncogene or cancer-related gene associated with a malignancy, or detection of immunocomplexes formed between the protein expression product and antibodies in body fluid, allows the diagnosis of the presence of a malignancy. The present invention also discloses methods and compositions for treating a malignancy.
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申请公布号 |
US5773230(A) |
申请公布日期 |
1998.06.30 |
申请号 |
US19950469081 |
申请日期 |
1995.06.05 |
申请人 |
WASHINGTON RESEARCH FOUNDATION |
发明人 |
CHEEVER, MARTIN A.;PEACE, DAVID J. |
分类号 |
G01N33/53;A61K35/14;A61K39/00;A61K48/00;A61P31/04;A61P35/00;C07K14/47;C07K14/82;C12N5/10;C12N15/00;C12N15/09;C12N15/12;C12P21/02;G01N33/50;G01N33/574;(IPC1-7):C12Q1/02 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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