Compounds for treating disorders of lipid metabolism and their preparation

摘要

The present invention relates to tertiary 4-amino-2-ureidopyrimidine-5-carboxamides of formula I: one or more H are replaced by F; R2 is selected from the group consisting of F, Cl, Br, H, -O-(C1-C8)-alkyl and (C1-C8)-alkyl, wherein one or more of the H of the alkyls can be replaced by F; R3 is selected from the group consisting of F, Cl, Br, H, -O-(C1-C4)-alkyl and (C1-C4)-alkyl, wherein one or more of the H of the alkyl can be replaced by F; R4 is CF3 or OCF3; and their physiologically tolerable salts. Process for preparing the compounds of formula I are also described. The compounds are suitable for the treatment of disorders of lipid metabolism.