<p>2125648 9312219 PCTABS00023 A process for the cultivation in continuous culture of a filamentous microorganism in a culture medium to which are supplied sources of carbon and other appropriate nutrients. The carbon or another nutrient source is supplied in an amount limiting to the growth of the culture and constitutes a limiting nutrient thereto. The development of an unwanted variant of the filamentous microorganism is restricted or delayed by supplying a first nutrient source to the culture as a limiting nutrient, and thus changing the nutrient supply to the culture in a manner such that a second nutrient source replaces the first nutrient source as the limiting nutrient.</p>
申请公布号
GR3026278(T3)
申请公布日期
1998.06.30
申请号
GR19980400268T
申请日期
1998.03.05
申请人
IMPERIAL CHEMICAL INDUSTRIES PLC
发明人
TRINCI, ANTHONY, PETER, JOSEPH;ROBSON, GEOFFREY, DAVID;WIEBE, MARILYN, GAIL;NAYLOR, THOMAS, WILLIAM