发明名称 Use of nk-1 receptor antagonists for treating major depressive disorders with anxiety
摘要 The present invention provides the use of an orally active, long acting, CNS-penetrant NK-1 receptor antagonist for the manufacture of a medicament adapted for oral administration for the treatment or prevention of major depressive disorder with anxiety without concomitant therapy with other anti-depressant or anti-anxiety agents, methods of treatment using such a NK-1 receptor antagonist and pharmaceutical compositions comprising the same.
申请公布号 AU5559198(A) 申请公布日期 1998.06.29
申请号 AU19980055591 申请日期 1997.11.25
申请人 MERCK SHARP & DOHME LIMITED 发明人 RAYMOND BAKER;NEIL ROY CURTIS;JASON MATTHEW ELLIOTT;TIMOTHY HARRISON;GREGORY JOHN HOLLINGWORTH;PHILIP STEPHEN JACKSON;JANUSZ JOZEF KULAGOWSKI;NADIA MELANIE RUPNIAK;EILEEN MARY SEWARD;CHRISTOPHER JOHN SWAIN;BRIAN JOHN WILLIAMS
分类号 A61K31/00;A61K31/395;A61K31/4015;A61K31/438;A61K31/445;A61K31/451;A61K31/535;A61K31/5375;A61K31/5377;A61K31/675;A61K45/00;A61P25/22;A61P25/24;A61P43/00;C07D211/56;C07D265/32;C07D413/06;C07D491/10;(IPC1-7):A61K31/535 主分类号 A61K31/00
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