| 发明名称 |
BOTULINUM TOXIN DERIVATIVES ABLE TO MODIFY PERIPHERAL SENSORY AFFERENT FUNCTIONS. |
| 摘要 |
The invention relates to an agent specific for peripheral sensory afferents. The agent may inhibit the transmission of signals between a primary sensory afferent and a projection neuron by controlling the release of at least one neurotransmitter or neuromodulator from the primary sensory afferent. The agent may be used in or as a pharmaceutical for the treatment of pain, particularly chronic pain.
|
| 申请公布号 |
MX9708124(A) |
申请公布日期 |
1998.06.28 |
| 申请号 |
MX19970008124 |
申请日期 |
1997.10.21 |
| 申请人 |
THE SPEYWOOD LABORATORY LIMITED;MICROBIOLOGICAL RESEARCH AUTHORITY |
发明人 |
KEITH ALAN FOSTER;MICHAEL JOHN DUGGAN;CLIFFORD CHARLES SHONE |
| 分类号 |
C12N15/09;A61K35/74;A61K38/00;A61K38/16;A61K38/22;A61K38/46;A61K38/48;A61K39/395;A61K47/48;A61P25/00;A61P25/04;C07K14/33;C07K14/48;C07K19/00;C12N9/52;C12N15/31;C12N15/62;C12P21/02;(IPC1-7):C12N15/31;C12N09/52;C07K14/475;C07K14/52;C07K14/575;C07K16/18 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
