发明名称 THE TREATMENT OF HIV AND OTHER VIRAL INFECTIONS USING COMBINATORY THERAPY.
摘要 Novel antiviral combinations for the treatment or prevention of viral infections, in particular, HIV, are disclosed. This new antiviral therapy employs either DP-178 or DP-107, viral fusion inhibitors, in combination with at least one other antiviral therapeutic agent. The combinations of the invention are better than single therapies alone, and in certain cases are synergistic. The use of DP-178 or DP-107 is an ideal therapy to combine with another antiviral, given both the novel mechanism which this therapeutic blocks HIV transmission and the non-toxicity of the therapeutic.
申请公布号 MX9709682(A) 申请公布日期 1998.06.28
申请号 MX19970009682 申请日期 1997.12.05
申请人 TRIMERIS, INC. 发明人 ROSS M. JOHNSON;DENNIS M. LAMBERT
分类号 A61K45/00;A61K31/505;A61K31/52;A61K38/00;A61K38/16;A61K38/19;A61K38/21;A61P31/12;C07K14/16;(IPC1-7):A61K38/00;A61K38/02;C07K01/00;C07K05/00;C07K07/00;C07K17/00 主分类号 A61K45/00
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