| 摘要 |
<p>Methods and apparatus for the measurement of oxygen, pH and CO2 in human and animal tissue is provided in which the compounds preferably comprise a chromophore and/or fluorphor capable of absorbing an amount of energy and subsequently releasing the energy as phosphorescent and/or fluorescent light, and wherein the phosphorescence is quenched by molecular oxygen according to the Stern-Volmer relationship. CO2 is measured by a fluorphor which alters fluorescence with pH. The apparatus includes an optical fiber (2) for transmitting light to a probe (70) that includes a gas permeable film (10) enclosing a portion (12) of the distal end of the optical fiber to form a reservoir (14) of a solution of the oxygen quenchable phosphorescent compound and/or the fluorescence emitting compound. The apparatus also includes a light source (36) and a light detector (34).</p> |
