发明名称 |
HUMAN AND MAMMALIAN DNA REPLICATION ORIGIN CONSENSUS SEQUENCES |
摘要 |
The present invention relates to a human or mammalian DNA replication origin consensus sequence which consists of a sequence selected from the group consisting of CCTMDAWKSGBYTSMAAWYWBCMYTTRSCAAATTCC (SEQ ID NO:1); and AWMTWAAKRAWRWWKKDAVWWGAKRWWKWVWHRASSACMDWKAAKTWKGGWTWARRYWKGRKMWWTWKAWSDATAKWWW KDAKWKMWRKTT (SEQ ID NO:4). A method for the control of initiation of mammalian DNA replication which comprises the steps of: a) inserting a consensus sequence coding for a sequence of the present invention together with a DNA fragment to form a vector capable of expression of the DNA fragment; b) introducing the vector of step a) into mammalian cells in vitro.
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申请公布号 |
CA2274306(A1) |
申请公布日期 |
1998.06.25 |
申请号 |
CA19972274306 |
申请日期 |
1997.12.12 |
申请人 |
MCGILL UNIVERSITY |
发明人 |
NIELSEN, TORSTEN O.;COSSONS, NANDINI H.;ZANNIS-HADJOPOULOS, MARIA;PRICE, GERALD B. |
分类号 |
C12N15/09;A61K48/00;C07K14/47;C12N15/85;(IPC1-7):C12N15/85;C12N15/11;C12N15/90 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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