发明名称 SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1 BETA CONVERTING ENZYME INHIBITORS
摘要 PCT No. PCT/US97/18406 Sec. 371 Date Apr. 9, 1999 Sec. 102(e) Date Apr. 9, 1999 PCT Filed Oct. 9, 1997 PCT Pub. No. WO98/16504 PCT Pub. Date Apr. 23, 1998The present invention relates to compounds that are inhibitors of interleukin-1 beta converting enzyme that have the Formula I, II, or III. This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock reperfusion injury, Alzheimer's disease, and shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1 beta converting enzyme.
申请公布号 WO9816504(A3) 申请公布日期 1998.06.25
申请号 WO1997US18406 申请日期 1997.10.09
申请人 WARNER-LAMBERT COMPANY;ALLEN, HAMISH, JOHN;BRADY, KENNETH, DALE;HARTER, WILLIAM, GLEN;LUNNEY, ELIZABETH, ANN;PLUMMER, MARK, STEPHEN;SAWYER, TOMI;SHAHRIPOUR, AURASH;WALKER, NIGEL 发明人 ALLEN, HAMISH, JOHN;BRADY, KENNETH, DALE;HARTER, WILLIAM, GLEN;LUNNEY, ELIZABETH, ANN;PLUMMER, MARK, STEPHEN;SAWYER, TOMI;SHAHRIPOUR, AURASH;WALKER, NIGEL
分类号 A61K31/192;A61K31/341;A61P1/00;A61P7/08;A61P19/02;A61P25/28;A61P31/04;C07C311/19;C07C311/29;C07C311/46;C07C323/67;C07D307/12 主分类号 A61K31/192
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