摘要 |
PCT No. PCT/US97/18406 Sec. 371 Date Apr. 9, 1999 Sec. 102(e) Date Apr. 9, 1999 PCT Filed Oct. 9, 1997 PCT Pub. No. WO98/16504 PCT Pub. Date Apr. 23, 1998The present invention relates to compounds that are inhibitors of interleukin-1 beta converting enzyme that have the Formula I, II, or III. This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock reperfusion injury, Alzheimer's disease, and shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1 beta converting enzyme. |
申请人 |
WARNER-LAMBERT COMPANY;ALLEN, HAMISH, JOHN;BRADY, KENNETH, DALE;HARTER, WILLIAM, GLEN;LUNNEY, ELIZABETH, ANN;PLUMMER, MARK, STEPHEN;SAWYER, TOMI;SHAHRIPOUR, AURASH;WALKER, NIGEL |
发明人 |
ALLEN, HAMISH, JOHN;BRADY, KENNETH, DALE;HARTER, WILLIAM, GLEN;LUNNEY, ELIZABETH, ANN;PLUMMER, MARK, STEPHEN;SAWYER, TOMI;SHAHRIPOUR, AURASH;WALKER, NIGEL |