摘要 |
<p>A method of preparing a concentrated solution of a carrier-free radioisotope which includes the steps of: a) providing a generator column (11) loaded with a composition containing a parent radioisotope; b) eluting the generator column (11) with an eluent solution which includes a salt of a weak acid to elute a target daughter radioisotope from the generator column in a first eluate; c) eluting a cation-exchange column (15) with the first eluate to exchange cations of the salt for hydrogen ions and to elute the target daughter radioisotope and a weak acid in a second eluate; d) eluting an anion-exchange column (35) with the second eluate to trap and concentrate the target daughter radioisotope and to elute the weak acid solution therefrom; and e) eluting the concentrated target daughter radioisotope from the anion-exchange column (35) with a saline solution.</p> |