AAV SPLIT-PACKAGING GENES AND CELL LINES COMPRISING SUCH GENES FOR USE IN THE PRODUCTION OF RECOMBINANT AAV VECTORS

摘要

The present invention provides AAV "split-packaging" genes, and packaging cells comprising such genes, for use in the production of high titers of replication-incompetent recombinant AAV vectors that can be used to deliver transgenes of interest to a variety of mammalian cells.