摘要 |
<p>The present invention provides anti-obesity proteins wherein at least one of the Trp 100 or Trp 138 is replaced by Glu, Asp, His, Lys or Arg, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type 2 diabetes, cardiovascular disease, and cancer.</p> |