发明名称 ANTAGONISTS OF THE ONCOGENIC ACTIVITY OF THE PROTEIN MDM2, AND USE THEREOF IN THE TREATMENT OF CANCERS
摘要 The present invention relates to the utilization of a compound capable of antagonizing at least partially the oncogenic activity of the protein Mdm2 for the preparation of a pharmaceutical composition intended more particularly to a treatment of cancers with no p53 context. It further relates to the viral vector comprising a nucleic acid sequence coding for a compound capable of inhibiting at least partially the oncogenic activity of the protein Mdm2, and to a corresponding pharmaceutical composition.
申请公布号 EP0848720(A2) 申请公布日期 1998.06.24
申请号 EP19960930195 申请日期 1996.09.02
申请人 RHONE-POULENC RORER S.A.;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 发明人 TOCQUE, BRUNO;DUBS-POTERSZMAN, MARIE-CHRISTINE;WASYLYK, BOHDAN
分类号 C12N15/09;A61K31/00;A61K38/00;A61K45/00;A61P35/00;C07K14/47;C07K14/82;C07K16/00;C07K16/32;(IPC1-7):C07K14/82 主分类号 C12N15/09
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