发明名称 |
Method for treating leukemia with a hexa-cyclic compound |
摘要 |
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: <IMAGE> The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumor activity and a high degree of safety, and can be applied as an antitumor medicine for curing tumors of various kinds.
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申请公布号 |
US5770605(A) |
申请公布日期 |
1998.06.23 |
申请号 |
US19970811239 |
申请日期 |
1997.03.03 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD.;KABUSHIKI KAISHA YAKULT HONSHA |
发明人 |
TERASAWA, HIROFUMI;EJIMA, AKIO;OHSUKI, SATORU;UOTO, KOUICHI |
分类号 |
C07D491/22;C07D495/22;(IPC1-7):A61K31/47 |
主分类号 |
C07D491/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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