发明名称 |
Peptides for reducing or inhibiting bone resorption |
摘要 |
The present invention provides Arg-Gly-Asp peptides that can reduce or inhibit the binding of osteoclasts to a matrix such as bone or can selectively alter integrin receptor binding. The invention also provides methods of using the Arg-Gly-Asp peptides to reduce or inhibit osteoclast binding to a matrix, to reduce or inhibit bone resorption in a subject and to alter alpha V beta 3 binding.
|
申请公布号 |
US5770565(A) |
申请公布日期 |
1998.06.23 |
申请号 |
US19940303052 |
申请日期 |
1994.09.08 |
申请人 |
LA JOLLA CANCER RESEARCH CENTER |
发明人 |
CHENG, SOAN;INGRAM, RONALD;MULLEN, DANIEL;TSCHOPP, JUERG |
分类号 |
A61K38/00;A61P3/02;A61P9/10;A61P43/00;C07K5/10;C07K7/06;C07K7/08;C07K14/75;C07K14/78;(IPC1-7):A61K38/08;A61K38/10 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|