发明名称 |
Synthetic antibody mimics-multiple peptide loops attached to a molecular scaffold |
摘要 |
A synthetic antibody mimic comprising multiple peptide loops built on an organic or molecular scaffold. In a highly preferred embodiment of the invention, a calixarene unit comprises the organic scaffold to which is attached a plurality of peptide loops. The antibody mimics allow for the generation of large libraries of artificial antibodies that can be screened for binding to target antigens.
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申请公布号 |
US5770380(A) |
申请公布日期 |
1998.06.23 |
申请号 |
US19960712521 |
申请日期 |
1996.09.13 |
申请人 |
UNIVERSITY OF PITTSBURGH |
发明人 |
HAMILTON, ANDREW D.;HAMURO, YOSHITOMO |
分类号 |
C07K7/02;(IPC1-7):G01N33/53;C07K5/02 |
主分类号 |
C07K7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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