发明名称 |
Lys - plasminogen in the prevention and treatment of ischemia and reperfusian injury |
摘要 |
<p>A treatment of ischemia and the attendant reperfusion injury entails the administration plasmin and plasmin-forming proteins, including lys-plasminogen and similar substances. Lys-plasminogen, which can be obtained from the proteolytic cleavage of glu-plasminogen, has been found to have a protective effect on tissue that has been injured by ischemic conditions. The administration of lys-plasminogen can used to treat subjects during the time of reperfusion and after reperfusion has already occurred. Lys-plasminogen also can be administered in conjunction with clot lysis therapies, such as those that employ tissue plasminogen activator and the like. <IMAGE></p> |
申请公布号 |
EP0631786(B1) |
申请公布日期 |
1998.06.17 |
申请号 |
EP19940110267 |
申请日期 |
1994.07.01 |
申请人 |
IMMUNO AKTIENGESELLSCHAFT |
发明人 |
EIBL, JOHANN, DR.;PICHLER, LUDWIG, PROF.;SCHWARZ, HANS-PETER |
分类号 |
A61K38/00;A61K38/43;A61K38/46;A61K38/48;A61P9/00;A61P9/10;(IPC1-7):A61K38/48 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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