发明名称 MULTIMERIC RECOMBINANT UREASE VACCINE
摘要 Methods and compositions are provided for preventing and/or treating Helicobacter (e.g., H. pylori) infection. The compositions of the invention, which are used in the methods of the invention (which include mucosal administration of the compositions), include compositions containing multimeric complexes of recombinant, enzymatically inactive Helicobacter urease in a pharmaceutically acceptable carrier or diluent; and compositions containing (a) a Helicobacter antigen, and (b) an antibiotic, an antisecretory agent, a bismuth salt, or a combination thereof.
申请公布号 CZ9703426(A3) 申请公布日期 1998.06.17
申请号 CZ19970003426 申请日期 1996.04.25
申请人 ORAVAX 发明人 LEE CYNTHIA K.;MONATH THOMAS P.;ACKERMAN SAMUEL K.;THOMAS WILLIAM D. JR.;SOMAN GOPALAN;KLEANTHOUS HAROLD;WELTZIN RICHARD A.;PAPPO JACQUES;ERMAK THOMAS;GUIRAKHOO FARSHAD;BHAGAT HITESH;SUSSMAN ILENE
分类号 A61K51/00;A61K31/34;A61K31/415;A61K31/425;A61K31/557;A61K31/70;A61K38/46;A61K39/02;A61K39/39;A61K45/00;A61P1/00;A61P1/04;C12N9/14;C12N9/80 主分类号 A61K51/00
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