发明名称 Treatment of radiation-damaged bone marrow using galactosyl ceramides
摘要 The present invention relates to a pharmaceutical composition (a marrow cell proliferation accelerator, a radioprotective agent, a therapeutic agent for thrombocytopenia) comprising a compound represented by the following formula (A), and to a therapeutic or prophylactic method (a method for accelerating marrow cell proliferation, a method for protecting human against radiation damage, a method for the treatment of thrombocytopenia) characterized in that an effective amount of a compound represented by the following formula (A) is administered to human: <IMAGE> (A) wherein R2 represents s one of the substituents defined by the following (a) to (d): (a) -CH2(CH2)yCH3, (b) -CH(OH)(CH2)y(CH3)2, and (c) -CH(OH)(CH2)yCH(CH3)2, and (d) -CH=CH(CH2)yCH3 (wherein Y is an integer of 5-17).
申请公布号 US5767092(A) 申请公布日期 1998.06.16
申请号 US19950406061 申请日期 1995.03.17
申请人 KIRIN BEER KABUSHIKI KAISHA 发明人 KOEZUKA, YASUHIKO;KABAYA, KOJI;MOTOKI, KAZUHIRO
分类号 A61K31/70;C07H15/04;C07H15/10;(IPC1-7):A61K31/70 主分类号 A61K31/70
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