| 摘要 |
A combinatorial library is disclosed which is represented by Formula (T'L)q+E,crc S+EE C(O)L'II'' I +E,crc S+EE C(O)L'II'' I' or wherein: +E,crc S+EE is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. This library contains hydroxypropylamines of the formula:Aa1-Aa2-(CH2Ar1)-CH2CHOH-CH2XR1IIwherein: Aa1 and Aa2 is each an amino acid joined to each other through an amide bond; Ar1 is an aromatic ring system; -CH2Ar1 is attached to N on Aa2; and R1 is H, C1-20 alkyl, alkenyl, alkynyl, aryl, heteroaryl, aryl or heteroaryl fused to a 3- or 4-membered moiety to form a non-aromatic second ring, or substituted C1-20 alkyl, alkenyl, or alkynyl.
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