发明名称 Method for identification of high affinity nucleic acid ligands to selectins
摘要 This invention discloses high-affinity oligonucleotide ligands to lectins, specifically nucleic acid ligands having the ability to bind to the lectins, wheat germ agglutinin, L-selectin, E-selectin and P-selectin. Also disclosed are the methods for obtaining such ligands.
申请公布号 US5766853(A) 申请公布日期 1998.06.16
申请号 US19950472255 申请日期 1995.06.07
申请人 NEXSTAR PHARMACEUTICALS, INC. 发明人 PARMA, DAVID H.;HICKE, BRIAN JAMES;GOLD, LARRY
分类号 A61K38/00;C07B61/00;C07H19/06;C07H19/10;C07H21/00;C07K7/22;C07K14/00;C07K14/16;C07K14/72;C12N9/12;C12N15/10;C12N15/115;C12Q1/37;C12Q1/68;C12Q1/70;F02B75/02;G01N33/53;G01N33/531;G01N33/532;G01N33/535;G01N33/569;G01N33/68;G01N33/76;(IPC1-7):C12Q1/68;C07H19/00;C07H21/02 主分类号 A61K38/00
代理机构 代理人
主权项
地址