发明名称 Monoclonal antibodies to glycoprotein P
摘要 PCT No. PCT/EP93/01533 Sec. 371 Date Dec. 15, 1994 Sec. 102(e) Date Dec. 15, 1994 PCT Filed Jun. 16, 1993 PCT Pub. No. WO93/25700 PCT Pub. Date Dec. 23, 1993A monoclonal antibody that recognises a structurally continuous and extracellularly-located epitope of human P-glycoprotein is described. The monoclonal antibody has a continuous amino acid sequence, and a binding affinity for the P-glycoprotein which manifests in the ability to stain greater than 90% of live CEM-VBL10 cells in a flow cytometry assay.
申请公布号 US5766946(A) 申请公布日期 1998.06.16
申请号 US19940356272 申请日期 1994.12.15
申请人 INSTITUTO SUPERIORE DI. SANITA' 发明人 CIANFRIGLIA, MAURIZIO
分类号 G01N33/53;A61K38/00;A61K39/395;A61P35/00;C07K14/705;C07K16/28;C07K16/30;C12N5/20;C12N15/09;C12P21/08;G01N33/574;G01N33/577;(IPC1-7):C12N5/12 主分类号 G01N33/53
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