Oligodeoxynucleotides containing 5-alkyl, 5-(1-alkenyl)- and 5-(1-alkynl) pyrimidines

摘要

A 12 to 30 nucleotide-unit long oligonucleotide that comprises at least one 5-substituted uracil or cytosine, where the 5-substituent is a C3-6 n-alkyl, a vinyl, a butenyl, an ethynyl, or a C4-12 n-1-alkynyl, with the proviso that the uracil moiety may not be substituted with an n-alkyl or a C8-12 n-1-alkynyl.