PROCESS FOR PREPARING POLYNUCLEOTIDES, PRODUCT THUS OBTAINES AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME

摘要

This invention relates to a preparation process of polymers of nucleotides wherein a bacteria strain culture lysate is passed successively through three columns (ion exchange resin, hydrophobic resin and molecular sieve), whereby there is obtained a substantially pure polynucleotidephosphorylase solution. Further polymerisation by this agent leads to non toxic and non pyrogen products. This invention relates also to products thus obtained and to therapeutic compositions containing the same.