| 摘要 |
PROBLEM TO BE SOLVED: To obtain a skin preparation for external use having excellent substance P antagonist activities especially for skin, and further having high safety, and useful for improving symptom of various kinds of dermatosis by including a specific plant or an extract thereof. SOLUTION: This skin preparation for external use includes one or more kinds of plants selected from among Eucommia ulmoides, Eclipta prostrata and leaf of Phyllostachys nigra, or an extract thereof. The extract is preferably a water fraction obtained by extracting the plant with water and/or water-soluble organic solvent and fractionating the extract with water and ethyl acetate. A daily dose of the objective skin preparation for external use is preferably 10-5,000mg per adult in terms of the dried weight of the extract and administered by dividing to 1-4 times. |
