METHOD TO INCREASE AND MODIFY IMMUNE RESPONSES

摘要

Method for increasing the ability of an antigen, either by itself or in combination with an adjuvant, to obtain higher levels of immune responses and/or for modifying the immune responses. The method involves targeting antigens to macrophages via their scavenger receptors, either by modifying antigens by coupling one or more amino groups of the antigen with acyl and/or carboxyl groups with or without further adsorption on an adjuvant or by the co-adsorption of other scavenger receptor ligands on an adjuvant along with an antigen.