| 摘要 |
The present invention relates to a previously unknown receptor protein, named GITR (Glucocorticoid Induced TNFR-family Related protein), which shares structural and biological characteristics with other members of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. Also disclosed are splicing variants of GITR. The invention further relates to polynucleotide sequences encoding the GITR receptor and its splicing variants, vectors comprising such polynucleotide sequences, host cells transformed with the said vector and a recombinant process for producing the proteins of the invention.
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